AHR and early-onset autosomal dominant Alzheimer disease: However, the emergence of the AHR–microbiota axis prompted us to expand insights into other GI diseases, and AHR activity-related diseases including Alzheimer’s disease (Salminen, 2023), arthritis (Rosser et al., 2020), cardiovascular disease (Paeslack et al., 2022), psoriasis (Qiao et al., 2022), and so on.