(31) reported that tumor-associated macrophage-derived exosome-loaded miR-193a-5p promotes ccRCC vasculogenic mimicry and immune invasion by inhibiting TIMP metallopeptidase inhibitor 2 (TIMP2) transcription through specific sponging the 3' untranslated regions (3′UTR) of TIMP2. This evidence concerns the gene TIMP2 and neoplasm.