Notably, in the GSE146771 dataset encompassing 10 primary colorectal cancer patients and comprising 10,468 cells, ABI3 expression was widely distributed across various immune cell types, such as T cell isoforms, endothelial, NK cells, monocytes, and macrophages in the colorectal cancer (CRC) microenvironment, as illustrated in Figures 3B, C. Here, ABI3 is linked to colorectal carcinoma.