We then categorized tumor samples based on the median methylation levels, separating them into high and low methylation groups and found that high ABI3 methylation level patients had lower overall survival rates in ACC, KIRP, and KIRC, as well as lower survival rates in LGG, STAD, and UVM, as shown in Figure 5J. The gene discussed is ABI3; the disease is adrenal cortex carcinoma.