By way of including the two homozygous mutations (p.Glu231Asp and p.E231X) observed with neonatal diabetes in the works of Philippi et al. (2021), the one homozygous frameshift mutation (p.Met289Argfs*80) observed with neonatal diabetes in the works of Russ-Silsby et al. (2023), and the two homozygous mutations p.H33Q and p.P94P that we observed with MODY, T1D and T2D, a total of 5 homozygous mutations have been reported so far in ONECUT1 gene as relating to the clinical diversity in diabetes (Supplementary Figure S2). Here, ONECUT1 is linked to type 2 diabetes mellitus.