ABCG5 and gallstones: It has been reported that the ABCG5/8 (encoding the hepatobiliary cholesterol transporter 5/8) allele is related to the recurrence of choledocholithiasis, and the variant gene ABCG D19H is currently recognized as a genetic risk factor for the formation of gallstones, which can effectively predict the recurrence of choledocholithiasis [8].