After further adjustment for each other in multivariate analysis, high MASP-2 was independently associated with an increased risk of GDM, whereas the OR of high vs. low MASP-1 for GDM was no longer significant (OR: 2.62, 95% CI: 1.44-4.77 and 1.37, 0.83-2.29, respectively) (Table 2). This evidence concerns the gene MASP2 and gestational diabetes.