MEFV and hereditary spastic paraplegia: However, only IBD and asthma patients had the MEFV gene mutation.46 In contrast to our results, a study among 95 Egyptian patients mentioned that 13.68% of their patients had other inflammatory conditions such as JIA (n=4, 4.21%), HSP in (n=3, 3.16%), SLE (n=3,3.16%), and IBD (n=2, 2.11%), while the most frequent correlated mutation was M680I followed by E148Q, V726A and M694V mutations.20