The gene locus of the cell adhesion molecule NrCAM, which regulates fasciculation of mouse brain commissures, shows distinct polymorphisms associated with ASDs (Pinto et al., 2010; Voineagu et al., 2011; Sakurai, 2012), while its knockout in male mice exhibits autism-related behaviors (Moy et al., 2009). Here, NRCAM is linked to autism.