Moreover, in applying our observation to publically available patient data [Breast Invasive Carcinoma- TCGA, PanCancer Atlas (47)] using cBioportal (46, 52), we can see that there is a low but statistically significant positive correlation between the mRNA expression of COL1A1 and the level of phosphorylation of Annexin A2 at Tyr 24 (Spearman’s correlation, r = 0.2429, p = 0.0160). Here, COL1A1 is linked to invasive breast carcinoma.