For example, one group analyzed the serum levels of lncRNA-ATB, which can be activated by TGF-β, and FAM83H-AS1 in EBC patients and healthy controls, ultimately determining that lncRNA-ATB is superior to other tumor antigens such as CA15-3 when used to identify patients with stage I-II disease, whereas FAM83H-AS1 levels were related to tumor volume and metastatic progression to the lymph nodes (73). Here, SACK1H is linked to neoplasm.