Conversely, the expression of BNP decreased in both the dynamic and dynamic + TGF‐β1 conditions, and the expression of NPRA diminished when both stimulations were combined, confirming the previously reported involvement of BNP and NPRA in modulating myocardial fibrosis[39] (Figure 3c,xii,xiii). This evidence concerns the gene NPR1 and Myocardial fibrosis.