TLR4 and infection: These variables included: (i) the spore dose required to establish infection; (ii) the impact of humidity on infection as humidity is particularly critical for fungal sporulation, germination, and invasion of insect hosts [32]; (iii) the time of onset, magnitude, and efficacy of the Toll immune response; (iv) the period of time preceding death when the host is immobilized (immobilization time); (v) the interval between death and the onset of sporulation; and (vi) sporulation capacity per cadaver.