The top 10 keywords are listed as shown in Figure 8A, which are bile acids (213), nonalcoholic steatohepatitis (156), Farnesoid x receptor (137), fatty liver disease (121), expression (108), insulin resistance (107), metabolism (99), gut microbiota (88), inflammation (86) and mice (82). This evidence concerns the gene INS and metabolic dysfunction-associated steatohepatitis.