VAV1 and infection: In contrast to Mst1−/−Mst2fl/fl Vav–Cre mice, Mst1fl/flMst2fl/fl Lyz2–Cre mice (with Mst1 and Mst2 conditionally knocked out in myeloid cells) that were raised under standard SPF (specific pathogen-free) conditions for 7 months did not exhibit inflammation or infection.