On the other hand, genetic variations (HSD17B13 and TM6SF2) linked to NAFLD possess the capacity to modulate steroid levels and impact autophagy and mitochondrial function in the liver, which subsequently influence the expression or functionality of genes associated with oxidative stress, inflammation, or telomere maintenance [44–46]. The gene discussed is TM6SF2; the disease is metabolic dysfunction-associated steatotic liver disease.