PTPRC and neoplasm: We identified eight main cell populations based on their marker genes (Fig. 1c, Additional file 3: Fig. S3a): T helper cells (Th, N = 12,416), tumor-associated macrophages (TAM, N = 10,838), effector T cells (Teff, N = 6605), exhausted T cells (Tex, N = 5241), regulatory T cells (Treg, N = 3531), B cells (N = 5720), plasma cells (N = 3714) and myeloid-derived suppressor cells (MDSC, N = 1009) from the CD45 + dataset.