Representative IHC-stained sections are shown in Fig. 9B. Immunohistochemical analysis of tumor tissues from 60 ChRCC patients showed a significant association between higher expression of TFRC (P = 0.026; Fig. 9C) and SLC7A11 (P = 0.004; Fig. 9D) and a more advanced stage. Here, SLC7A11 is linked to chromophobe renal cell carcinoma.