In the population of individuals with early and late dry AMD according to CARMS 2–4, the proportion of CD4+ T cells in individuals with the at-risk HH SNP was 39.9% (11.9), which was significantly lower compared to 46.4% (11.3) in individuals with the YY SNP (P = 0.046) and 47.5% (10.2) with YH SNP (P = 0.004). The gene discussed is CD4; the disease is dry age related macular degeneration.