In enrichment analysis using gene ontology terms, these proteins were enriched in 2 terms related to molecular function, nerve growth factor binding (SORT1 and FURIN; P = 0.0043; fold enrichment = 112.8) and neurotrophin binding (SORT1 and FURIN; P = 0.013; fold enrichment = 56.4) implicated in the pathogenesis of atherosclerosis. The gene discussed is BDNF; the disease is atherosclerosis.