FURIN and myocardial ischemia: In addition to discovery of potential novel drug targets, large-scale proteomics and genetic data in diverse populations should improve risk prediction, early detection, and prevention strategies of IHD and many other diseases.PerspectivesCOMPETENCY IN MEDICAL KNOWLEDGE: Integrated analyses of proteomic and genetic data in prospective studies or diverse populations identify FURIN and other proteins as novel potential targets for treatment of IHD.