ACAT2 and colorectal carcinoma: For instance, circLDLR has been found to be overexpressed in CRC, and can upregulate the expression of SOAT1 by sponging miR‐30a‐3p, which modulated the cholesterol levels and facilitated the malignant progress of CRC.[156] Moreover, circRPL23A was downregulated in clear cell renal cell carcinoma (ccRCC) to promote cell proliferation, migration, and invasion by enhancing miR‐1233‐mediated repression of ACAT2 expression.