ACLY and gastric cancer: Mechanistically, TINCR interacts with ACLY directly and inhibited its ubiquitin degradation to increase cellular total acetyl‐CoA levels for lipid synthesis and histone acetylation.[103] Moreover, lncRNA FLJ22763, which is downregulated in gastric cancer (GC), negatively regulates the mRNA and protein expression of ACLY to suppress the proliferation, migration, and invasion of GC cells as a tumor suppressor gene.[104]