However, the mechanisms of these two lncRNAs in regulating FASN expression need to be further explored in detail.[115, 116] Recently, a novel lncRNA FASRL has been identified to promote the proliferation and metastasis of hepatocellular carcinoma (HCC) via directly binding ACACA (acetyl‐CoA carboxylase 1) to facilitate de novo synthesis of fatty acid.[117]. The gene discussed is NQO1-DT; the disease is hepatocellular carcinoma.