All of them have been shown to be dysregulated in various cancers, promoting the resistance of cancer cells to energy stress.[54, 55] For instance, as one of the rate‐limiting enzymes in FAO, CPTI can convert FA‐CoA into the carnitine derivatives to enter into the routes of mitochondrial and peroxisomal β‐oxidation.[56, 57] No surprisingly, it has been found to be highly correlated with poor prognosis of patients with acute myeloid leukemia (AML) or ovarian cancer.[36, 53]. The gene discussed is CPT1A; the disease is acute myeloid leukemia.