Mechanically, circRIC8B increased the expression of lipoprotein lipase (LPL) by directly binding miR‐199b‐5p, which further promoted cellular lipoproteins uptake and the hydrolysis of triglycerides (TGs) to facilitate the progression of CLL.[162] Moreover, Acyl‐CoA thioesterase 7 (ACOT7) plays a role in the lipolysis by converting Arachidonyl‐CoA to arachidonic acid and CoA. Here, LPL is linked to B-cell chronic lymphocytic leukemia.