In the Measurement of Exercise Tolerance before Surgery Study, measures of functional capacity were assessed along with NT-proBNP (1347 participants).12 The discrimination (ROC AUC) for a composite of 30-day mortality and myocardial infarction was 0.67 for the RCRI plus DASI and 0.65 for the RCRI plus NT-proBNP (95% CI not reported). This evidence concerns the gene NPPB and myocardial infarction.