In addition to confirming the moderate ROC AUC (0.73; 95% CI, 0.68-0.79) for in-hospital MACE for RCRI plus NT-proBNP previously described by Duceppe et al,8 in the present cohort we report discrimination in the same order of magnitude when NT-proBNP was added to the NSQIP MICA, another commonly used clinical risk score.6,18 In the Measurement of Exercise Tolerance before Surgery study (including 1347 participants),12 the discrimination (ROC AUC) for a composite of 30-day mortality and myocardial infarction was 0.65 for the RCRI plus NT-proBNP. The gene discussed is NPPB; the disease is myocardial infarction.