RELB and hyperinsulinemic hypoglycemia, familial, 4: Neutralizing AAN-I-IFNs were detected in post-transplant samples from two out of the three other patients with RELB deficiency (Q72Tfs*152 and Y397*, 6 and 2.5 years after HSCT, respectively), whereas no such autoantibodies were detected in a patient with autosomal-recessive c-REL deficiency over a period of 7 years after HSCT, or in children with inborn errors of T-cell-intrinsic or neutrophil-intrinsic immunity or of erythrocyte function (n = 20), up to 15 years after transplantion (Supplementary Table 5 and Extended Data Fig. 7n).