The specific markers that have been applied are creatine kinase isoenzyme MB (CK-MB), cardiac troponin T (cTnT), cardiac troponin I (cTnI), and myoglobin, but they are released from the myocardium at a later stage of AMI occurrence and do not allow early ischemia diagnosis [111, 112]. The gene discussed is TNNI3; the disease is ischemia.