On the other hand, the genes with the greatest difference in expression between 10y-noCHF and 10y-MMVD-CHF dogs were three genes, MYH1, LOC102724058, and CNTN3, which were not part of the identified gene networks, i.e., they were not part of an orchestrated response to disease. The gene discussed is CNTN3; the disease is congestive heart failure.