Venn diagrams showing the number of early-stage, late-stage and all-stage HCC cases detected by AFP, PIVKA-II, and GAAD found that GAAD detected 8 more HCC cases (early and late), which were missed by the AFP + PIVKA-II combination (Supplemental Figure 4, http://links.lww.com/HC9/A643). Here, AFP is linked to hepatocellular carcinoma.