The expression of atherosclerosis-associated modulation markers Lgals3, Fn1, and Serpine1 (encoding PAI1) was increased at baseline and with 2.5 μg/mL MBD-Chol in the PcntSMC–/– SMCs, but these markers did not increase in the WT SMCs until 10 μg/mL MBD-Chol (Figure 4A). Here, SERPINE1 is linked to atherosclerosis.