The invasion assays illustrated that ectopic overexpression of SLC25A21 markedly suppressed cell invasion in KRAS-mutant CRC cells (M5 cells, P = 0.0012; SW620 cells, P < 0.0001) but not in Caco-2 cells (P = 0.9546, Figure 2H). The gene discussed is SLC25A21; the disease is colorectal carcinoma.