PDLIM7 and cancer: The potential pathogenic Type 1 + V3 haplotype is associated with diverse malignant neoplasms worldwide, and recently, this haplotype was shown to confer a functional increase in lytic reactivation due to the V3 polymorphism located in the promoter of the lytic transactivator gene BZLF1. 8All these findings indicate that the variants related to the African Raji strain can harbour unique synapomorphies, such as in the LMP1 oncogene.18