In addition, subgroup analysis of UTI status demonstrated that the effect size of PCa risk associated with PSA cutoffs was comparable between the original case–control population and patients without UTI (OR = 10.89, 11.51, 10.30, 9.65, and 9.35 for cutoffs of 4 ng/mL, 75th, 90th, 95th, and 99th percentiles, respectively; Table S6). The gene discussed is KLK3; the disease is bacterial urinary tract infection.