Our results are concordant with the previous studies [25-27]. DA was shown to reduce tumor growth, metastasis, and tumor angiogenesis [25]. Similar to the present study, Wu et al. (2020) showed that DA blocked the expression of NF-κB and reduced inflammation [27]. Prolonged inflammation stimulates the immune cells to secret a lot of inflammatory cytokines (such as IL-1, IL-6, and TNF-α) [28]. Our results showed that DA could suppress a few of those pro-inflammatory markers in KB cells. Previously, we showed that dopamine substantiated BCl-2 in A549 cells[4]. This evidence concerns the gene TNF and neoplasm.