TMEM119 and osteosarcoma: The knockdown of TMEM119 in the osteosarcoma cell lines U2OS and MG63 decreased cell proliferation by inhibiting the G1/S transition and also led to a decrease in the expression of Bcl2 and an increase in the expression of caspase 8 and caspase 9 most likely participating in the induction of apoptosis and suppressed tumorigenesis in vivo in nude mice and also decreased the ability of cell migration and invasion.