Lastly, we examined the spatial expression profile of ATR utilizing the Freiburg spatial transcriptomic atlas, which comprises 16 de novo glioblastoma specimens.34 ATR expression was observed to be associated with histological regions, including pseudopalisading, perinecrotic areas, and microvascular proliferation, as classified by the Ivy glioblastoma atlas. The gene discussed is ATR; the disease is glioblastoma.