CD34 and acute myeloid leukemia: The same results were also replicated from another proteomic cohort [53] where PDP1 protein was higher in the leukemic stem/progenitor cell-enriched CD34+ compartment of FLT3-ITD compared to FLT3-WT AML samples, and this difference was even more significant when compared to healthy CD34+ hematopoietic progenitor cells (HSPCs) (Fig. 2G).