SHBG and obesity due to melanocortin 4 receptor deficiency: In the sensitivity analysis of the reproductive hormone levels excluding participants who had blood drawn in the evening, results attenuated slightly and led to the loss of statistical significance for the association between maternal pre-pregnancy obesity and SHBG (−11% (95% CI: −22%; 2%)) and LH (8% (95% CI: −3%; 21%)) (Supplementary Table S3).