Skeletal muscle mass is a major driver of insulin sensitivity74 and known to be reduced across the lifespan in humans with FGR.4 Recent work showed improved muscle strength with Akkermansia supplementation in a mouse model of muscle atrophy.75 Additional studies are needed in the FGR population to determine whether Akkermansia depletion may be related to short- and long-term outcomes. Here, INS is linked to muscle atrophy.