The IPA analysis showed the involvement of the following canonical pathways, G1/S checkpoint regulation (FDR-corrected P value = 1.37 × 10–10), PI3K/AKT signalling (FDR-corrected P value = 2.48 × 10–10), ovarian cancer signalling (FDR-corrected P value = 3.37 × 10–10), and PTEN signalling (FDR-corrected P value = 6.87 × 10–10), with molecular mechanisms of cancer (FDR-corrected P value = 2.09 × 10–11) at the top of the list (Supplementary Figs. S2B and S3A). The gene discussed is AKT1; the disease is cancer.