In addition to the replicative senescence model, we also investigated SGF29 condensates in two genetically-driven models of premature aging: Hutchinson-Gilford Progeria Syndrome hMPCs (HGPS-hMPC, LMNAG608G/+ and LMNAG608G/G608G) and Werner Syndrome hMPCs (WS-hMPC, WRN–/–)49–54, in which hMPCs exhibit genetically accelerated senescence (Supplementary Fig. S2a–d). This evidence concerns the gene WRN and Werner syndrome.