CXCL10 and COVID-19: SARS-CoV-2 has the ability to infect human adipose tissue (Table 2), targeting both mature adipocytes and a subset of inflammatory adipose tissue-resident macrophages and stromal vascular cells, leading to immune activation and the secretion of inflammatory factors associated with severe COVID-19, including interferon-γ-induced protein-10 (IP-10), platelet-derived growth factor AA, platelet-derived growth factor AB/BB, IL-4, macrophage migration inhibitory factor, vascular endothelial growth factor A, and macrophage colony-stimulating factor 1 (174) (Fig. 1).