Only in two studies [16,25], visfatin levels in GCF were compared between gingivitis patients and healthy individuals, and 20 healthy cases and 30 gingivitis patients were included in the analysis, and SMD was estimated as 2.60 ng/ml (95% confidence interval (CI): -0.40–5.62, p = 0.090) (Table 2). This evidence concerns the gene NAMPT and gingivitis.