Then we found that these immune cell infiltrations markedly impacted the survival outcome of glioma patients, high expression levels of 3 immune cells (T-cell CD4 memory resting, NK cell activated and Monocytes) tended to have a better prognosis of glioma patients significantly, however, the opposite resulted in Macrophages M0 (Figure 8B). This evidence concerns the gene CD4 and glioma.