In clinical circumstances, the presence of CLCs or a rise in the local galectin-10 concentration might serve as an alternative sign of extensive occurrences of EETosis [8, 114]. EETs and CLCs are abundant in the mucosa and mucus of both CRSsNP and CRSwNP and are linked with type 2 inflammation [67, 90, 115]. The gene discussed is CLC; the disease is chronic rhinosinusitis with nasal polyps.