Sera from 120 patients with APS were examined and over 80% of APS patients showed anti-β2GPI/HLA-DR7 antibodies.51 Considering these results, using β2GPI/HLA-DR7 complex as an assay antigen is enough to analyze the prevalence of anti-β2GPI/HLA-DR antibodies in patients with APS. Here, APOH is linked to autoimmune polyendocrinopathy.