PNMA2 and paraneoplastic neurologic syndrome: Paraneoplastic neurological syndrome (PNS)-Ab tests found high titer GAD65 Abs in serum (positive immunoblot assays),[5] while Zic4, Tr (DNER), SOX1, Ma2, Ma1, Amphiphysin, CV2, Ri, Yo, and Hu antibodies were negative.