The 5 pathways include Coronavirus disease-COVID-19(degree = 18), AGE-RAGE signaling pathway in diabetic complications (degree = 17), IL-17 signaling pathway (degree = 14), Human cytomegalovirus infection (degree = 14) and Th17 cell differentiation(degree = 13) (see Table 3 for details). This evidence concerns the gene IL17A and cytomegalovirus infection.