On the other hand, based on the keyword emergence intensity indicated by “Strength,” “senile dementia” ranks first with an intensity index of 50.56; other keywords with significant prominence include circadian rhythm, Creutzfeldt Jakob disease, rem sleep, placebo controlled trial, tau, etc. These hot words have also become “strong hotspots” in academic tracking. The gene discussed is MAPT; the disease is Creutzfeldt Jacob disease.