TG and hypothyroidism: Studies have found that thyroid hormones can affect kidney function, resulting in abnormal serum uric acid levels in patients.[36]Studies have shown that hyperuricemia in patients with hypothyroidism is associated with decreased uric acid clearance, and its specific mechanism is caused by decreased renal plasma flow and glomerular filtration rate (GFR).[37]Thyroid hormone may be involved in renal uric acid clearance.