NEFL and snowflake vitreoretinal degeneration: However, there are limited studies evaluating the utility of elevated neurofilament light chain (NfL), a non‐specific marker of neuro‐axonal injury,17, 18 and glial acidic protein (GFAP), a marker of astroglial pathology due to neuronal damage,19 in predicting poorer WM health in SVD.