As expected, recurrent homozygous deletions in CDKN2A and RB1 were present in TCGA diffuse gliomas and GLASS progressed grade 4 IDHmut astrocytomas (Additional file 1: Table S8 and Table S11 and Additional file 2: Fig. S3c and S2f). Here, RB1 is linked to astrocytoma (excluding glioblastoma).