NRG3 and neoplasm: The NRG3 expression remained significant (hazard ratio 0.56 for the increase of NRG3 expression by its standard deviation, p = 0.024, Wald test) in a multivariate Cox proportional hazard model including also patient age and tumor grade as variables (Additional file 1: Table S9), or when using NRG3 expression alone (hazard ratio 0.49, p = 0.0026, Wald test).