TNC and ovarian serous carcinoma: Recently, it was demonstrated that transforming growth factor-beta-induced (TGFBI) protein and tenascin C (TNC) from ascites-derived TAMs promotes migration and progression of high-grade serous ovarian carcinoma (HGSC), characterized by a severe trans-coelomic tumor cell metastasis via the peritoneal fluid or malignant ascites [54].