However, the PMs subpopulation (SPM and LPM, Fig. 2D) from both WT and Mettl3-cKO mice had similar M1/M2 phenotyping during tumor progression (two to nine weeks), indicating that METTL3 is not involved in the M1 to M2 polarization during OC progression. Here, METTL3 is linked to neoplasm.