In addition, in humans, this gene was proved to be associated with glycosylated haemoglobin [99], a marker of average blood glucose levels. The gene Proline Rich 14 Like or PRR14L in this region is mainly studied in humans in the context of blood metabolism (increase in monocytes and decrease in neutrophils) and leukaemia gene expression profiles [100], whereas in sheep was proved to be differentially expressed between certain breeds [101]. This evidence concerns the gene PRR14L and leukemia.